Stochastic pulsing of gene expression enables the generation of spatial patterns in bacillus subtilis biofilms

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  • who: Eugene Nadezhdin from the Sainsbury LaboratoryUniversity of have published the Article: Stochastic pulsing of gene expression enables the generation of spatial patterns in Bacillus subtilis biofilms, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors use the B. subtilis general stress response pathway, mediated by the alternative sigma factor σB, as a model system to examine dynamic and heterogeneous gene_expression in biofilms. σB modulates more than 150 target genes in response to diverse stresses31,32. The authors examine σB expression in an isolate of B. subtilis capable of forming biofilms. Through modelling and . . .

     

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