Stoml2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing parl-induced pink1 degradation

HIGHLIGHTS

  • who: Cheng Qin from the (UNIVERSITY) have published the research work: STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation, in the Journal: (JOURNAL) of 11/08/2022
  • what: The authors reported that STOML2 was highly expressed in pancreatic tumor tissue but related to longer survival, which might support the idea that mitophagy could repress tumorigenesis but promote cancer progression .
  • how: The results indicated that the patients in the low STOML2 expression group had significantly shorter OS than those in the high STOML2 expression group in both . . .

     

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