Stress promotes rna g-quadruplex folding in human cells

HIGHLIGHTS

• who: Prakash Kharel from the (UNIVERSITY) have published the paper: Stress promotes RNA G-quadruplex folding in human cells, in the Journal: (JOURNAL)
• what: The authors propose that rG4s contribute to the preservation of rG4-bearing transcripts during stress, and intermolecular interactions between rG4-bearing transcripts and RNA-binding proteins could also promote the formation of stress-induced RNA-containing biomolecular condensates such as stress granules and P-bodies. Based on the data , the authors propose a model (Fig 4e) that the reversible stress-mediated increase in rG4s folding contributes to mRNA stability. The study . . .
  

   

  

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