Stromal structure remodeling by b lymphocytes limits t_cell activation in lymph nodes of mycobacterium tuberculosis-infected mice

HIGHLIGHTS

  • who: Lina Daniel and collaborators from the Faculty The University of Medicine, Shenzhen, China have published the research: Stromal structure remodeling by B lymphocytes limits T_cell activation in lymph nodes of Mycobacterium tuberculosis-infected mice, in the Journal: (JOURNAL)
  • what: The authors show that M. tuberculosis-infected mLN undergoes extensive structural changes driven by the disproportionate expansion of B lymphocytes. To determine whether peripheralization of transferred CD4+ T_cells occurs in the infected mLN, the authors focused on analyzing the cellular movement at the MR, as infected mLN had almost completely lost the IFRs . The authors . . .

     

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