Structural analysis of ppsp15 and pssp9 sand fly salivary proteins designed with a self-cleavable linker as a live vaccine candidate against cutaneous leishmaniasis

HIGHLIGHTS

• who: Mahya Sadat Lajevardi from the All the validated three-dimensional models were compared with original proteins (already modeled and validated by the same approach) using UCSF (University of California, San Francisco) Chimera v, software (https://u200bwww.u200bcgl.u200bucsf.u200bedu/u200bchimeu200bra/). The program makes a fit after detecting residues that should be paired. For this, the software utilizes secondary structures and sequences to overlap similar structures even with low similarity [28]. The result is evaluated using the rootmean-square deviation (RMSD) of atomic positions. Typically, RMSD is used as a quantitative measure of similarity between two or . . .
  

   

  

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