Structural and functional insights into the molecular mechanisms responsible for the regulation of pyruvate dehydrogenase kinase 2*

HIGHLIGHTS

  • who: Green Todd from the (UNIVERSITY) have published the Article: Structural and Functional Insights into the Molecular Mechanisms Responsible for the Regulation of Pyruvate Dehydrogenase Kinase 2*, in the Journal: (JOURNAL) of January/11,/2008
  • what: An important role played by PDHKs in the regulation of general metabolism prompted a number studies aimed at the structural characterization of this family of protein_kinases . RESULTS AND Discussion Structure of PDHK2-L2 and PDHK2-L2-App(NH)p Complexes-In this study, the authors determined the crystal_structure of PDHK2 complexed with either L2 or L2 and App(NH . . .

     

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