HIGHLIGHTS
- who: Ulysses Tsz Fung Lam from the (UNIVERSITY) have published the research: Structural and functional specificity of H3K36 methylation, in the Journal: (JOURNAL)
- what: The authors explore each of these determinants in more detail: Structural motifs in Set2/SETD2 in H3K36me catalysis Set2/SETD2 is a modular enzyme that hosts several wellconserved domains. In the next section, the authors explore the recent insights into how H3K36me crosstalk with DNA methylation, histone PTMs (acetylation and H3K27 methylation), and u00adN6-methyladenosine modifications on the RNA transcript.
- future: Structural and mutagenesis studies will be required to . . .
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