Structural basis for assembly and disassembly of the igf/igfbp/als ternary complex

HIGHLIGHTS

• who: Hyojin Kim from the (UNIVERSITY) have published the article: Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex, in the Journal: (JOURNAL) of 21/07/2022
• what: The authors report cryo-EM structure of the human IGF1/IGFBP3/ALS ternary complex, revealing the detailed architecture of a parachute-like ternary complex and crucial determinants for their sequential and specific assembly. The authors determined the cryo-EM structure of the human IGF1/ IGFBP3/ALS ternary complex. The authors show that the IGF1/IGFBP3 binary complex, in which IGF1 is clamped by . . .
  

   

  

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