Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01

HIGHLIGHTS

• who: Dora Pinto from the Institut e for Research in Biomedicine, Bellinzona, Ticino, Switzerland Lausanne University have published the research work: Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01, in the Journal: (JOURNAL) of November/13,/2019
• what: The authors examine the structural and molecular mechansims of neutralization by anti-MPER bnAb, LN01, which was isolated from lymph-node-derived germinal center B cells of an elite controller and exhibits broad neutralization breadth. The authors show that in addition to the MPER epitope, LN01 binding requires part . . .
  

   

  

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