Structural basis for high specificity of amadori compound and mannopine opine binding in bacterial pathogens*

HIGHLIGHTS

  • who: Loïc Marty from the (UNIVERSITY) have published the paper: Structural Basis for High Specificity of Amadori Compound and Mannopine Opine Binding in Bacterial Pathogens*, in the Journal: (JOURNAL) of October/21,/2016
  • what: The work demonstrates that AttC is not a mannopinebinding protein and reveals a specific binding pocket for DFG in SocA with an affinity in nanomolar range. The authors investigated and compared the structural and biochemical properties of two PBPs sharing 5% sequence identity, MotA and SocA, that have been associated with the assimilation of mannopine using genetic approaches (mapping of . . .

     

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