Structural basis for matriglycan synthesis by the large1 dual glycosyltransferase

HIGHLIGHTS

• who: Michael Katz and Ron Diskin from the Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, Israel Editor:, University of Liverpool have published the research: Structural basis for matriglycan synthesis by the LARGE1 dual glycosyltransferase, in the Journal: PLOS ONE of 10/07/2022
• what: Taken together, the authors propose that dimerization of LARGE1 is essential for its proper function in cells.
• future: Taken together under physiological conditions in cells LARGE1 is likely in the form of a parallel dimer but future in-vivo studies will need to corroborate this . . .
  

   

  

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