Structural basis for recognition of high mannose type glycoproteins by mammalian transport lectin vip36*

HIGHLIGHTS

  • who: Tadashi Satoh from the (UNIVERSITY) have published the Article: Structural Basis for Recognition of High Mannose Type Glycoproteins by Mammalian Transport Lectin VIP36*, in the Journal: (JOURNAL) of September/21,/2007
  • how: To demonstrate that the crystal_structure strictly represents the complex formed in solution the authors simulated a complex model of Man8(GlcNAc)2-Asn and VIP36 (Fig 8A).

SUMMARY

    The exoplasmic/luminal domain of VIP36 as well as the luminal domain of ERGIC-53 and Emp46/47p share homology with L (leguminous)-type lectins and are thus identified as . . .

     

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