Structural basis for the coiled-coil architecture of human ctip

HIGHLIGHTS

  • who: L. Pellegrini and collaborators from the London , AT, UKDepartment of Biochemistry, University of Cambridge, Cambridge , GA, UK have published the research: Structural basis for the coiled-coil architecture of human CtIP, in the Journal: (JOURNAL) of 05/09/2022
  • what: The authors show that the presence of the zinc-binding motif in the middle of the coil allows for the generation of distinct geometries of the CtIP N-terminus. royalsocietypublishing.org/journal/rsob towards NHEJ.
  • how: SEC-MALS data are presented with LS and dRI plotted alongside fitted molecular masses (Mr).
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