Structural basis for xenon inhibition in a cationic pentameric ligand-gated ion channel

HIGHLIGHTS

• who: Ludovic Sauguet and collaborators from the France, CEA, DSV/I BM, UMR, FranceEditor: Sheng Ye, Zhejiang University, CHINA have published the research work: Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion Channel, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0149795]. February 24, 2016 of February/24,/2016
• what: The authors characterize by X-ray crystallography the xenon-binding sites within both the open and "locally-closed" (inactive) conformations of GLIC.
• future: Investigations including a crystal_structure of GAs-bound GLIC in a desensitized form will be . . .
  

   

  

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