Structural basis of alpa-dependent transcription antitermination

HIGHLIGHTS

  • who: Aijia Wen et al. from the Department of Biophysics, and Department of Infectious Disease of Sir Run Run Shaw Hospital, Zhejiang University Immunity and Inflammatory diseases, Hangzhou, China have published the research: Structural basis of AlpA-dependent transcription antitermination, in the Journal: (JOURNAL) of December/18,/2021
  • what: The authors report the single-pArticle cryo-electron microscopy structures of both an AlpA-loading complex and an AlpAloaded complex.
  • future: Since the -10-like sequence of the transcription bubble is anchored to RNAP through ␴R2 further extension of the nascent RNA leads to . . .

     

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