HIGHLIGHTS
- who: Linlin Zhao from the (UNIVERSITY) have published the research work: Structural basis of interaction between the hepatitis C virus p7 channel and its blocker hexamethylene amiloride, in the Journal: (JOURNAL)
- how: Although the NMR data was collected for the p7 (5a) the high sequence identity between 5a and 1a and the fact that the p7 (5a) residues involved in HMA binding are mostly conserved in p7 (1a) provided the authors with strong confidence that the HMA binding_site reported in this study is relevant to the identified HMA inhibition and likely applicable to other p7 . . .
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