Structural basis of mitochondrial membrane bending by the i-ii-iii2-iv2 supercomplex

HIGHLIGHTS

• who: Alexander Mu00fchleip from the (UNIVERSITY) have published the research: Structural basis of mitochondrial membrane bending by the I-II-III2-IV2 supercomplex, in the Journal: (JOURNAL) of 28/06/2022
• what: The authors show that a supercomplex containing all four respiratory_chain components contributes to membrane curvature induction in ciliates. The authors report cryo-electron microscopy and cryo-tomography structures of the supercomplex that comprises 150 different proteins and 311 bound lipids, forming a stable 5.8-MDa assembly. Using molecular dynamics simulations, the authors demonstrate that the divergent supercomplex actively contributes to the membrane . . .
  

   

  

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