Structural basis of rapid actin dynamics in the evolutionarily divergent leishmania parasite

HIGHLIGHTS

  • who: Tommi Kotila from the Institute University of have published the research work: Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors focused on the Leishmania major parasite to elucidate the evolution of actin and actin-regulatory machinery, as well as to uncover how rapid actin dynamics can be achieved in divergent flagellated parasites in the absence of key actin-binding proteins. The authors show that L major actin filaments undergo much more rapid depolymerization at both barbed and pointed ends compared . . .

     

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