Structural basis underlying the synergism of nadase and slo during group a streptococcus infection

HIGHLIGHTS

  • who: Wei-Jiun Tsai from the Institute Kung University, Tainan, Taiwan have published the article: Structural basis underlying the synergism of NADase and SLO during group A Streptococcus infection, in the Journal: (JOURNAL) of 18/01/2023
  • what: The authors demonstrate that disruption of the interaction can affect the outcomes of GAS infection in vitro and in the mouse model. The authors demonstrate that disrupting the interaction between these two toxins impairs GAS cytotoxicity and intracellular survival (Fig 4).
  • how: The quantitative results are presented as median with interquartile range (n = 8). In . . .

     

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