Structural design and synthesis of novel cyclic peptide inhibitors targeting mycobacterium tuberculosis transcription

HIGHLIGHTS

• who: Filia Stephanie and collaborators from the Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas have published the Article: Structural Design and Synthesis of Novel Cyclic Peptide Inhibitors Targeting Mycobacterium tuberculosis Transcription, in the Journal: Life 2022, 1333 of 28/08/2022
• what: The authors conducted a computational screening to design novel cyclic peptide inhibitors that target the RIF binding_site of MTB RNAP. For this study, the 3D structure of this complex obtained fromare visualized Figure Forthe this study, the crystal . . .
  

   

  

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