HIGHLIGHTS
- who: Diego E. Sastre from the InstitutFacultad de Ciencias Esmeralda y Ocampo, Rosario, Argentina have published the Article: Structural determinant of functionality in acyl lipid desaturases, in the Journal: (JOURNAL) of 21/03/2018
- what: The authors took advantage of the high similarity of both Des and DesA with an inactive protein encoded by open_reading_frame (ORF) BL02692 (coding for a putative desaturase) from Bacillus licheniformis to design domainswapping and site-directed_mutagenesis experiments to elucidate the molecular basis of these observed differences. According to the model shown in Fig 5, nine histidine residues form the metal . . .
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