Structural disruption of baf chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program

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  • who: Carlos Jimu00e9nez from the Institute (VHIR), Universitat Autu00f2noma de Barcelona (UAB), Barcelona, Spain have published the Article: Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program, in the Journal: (JOURNAL)
  • what: This study aimed to understand the contribution of mSWI/SNF to the oncogenic epigenomes of neuroblastoma and its potential as a therapeutic target. The authors report a novel ATPase-independent role for the BAF complex in maintaining an epigenomic prou2011 gram that allows neuroblastoma invasiveness and metastasis urging for the development of new BAF pharmacologiu2011 cal structural . . .

     

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