Structural implications of mutations conferring rifampin resistance in mycobacterium leprae

HIGHLIGHTS

• who: Correction Publisher Correction from the (UNIVERSITY) have published the paper: Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae, in the Journal: (JOURNAL) of 22/03/2018
• what: The authors identified mutations corresponding to rifampin resistance in relapsed leprosy cases from three hospitals in southern India which treat leprosy patients. The model shows that rifampin binds to the β subunit of RNAP (Chain C) by forming five hydrogen_bonds with the sidechains of R454, R465 and N493, and the mainchain of Q438 and F439 (Fig 2).
• how: Similar observations were made in earlier . . .
  

   

  

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