Structural insights into antigen recognition of an anti-β-(1,6)-β-(1,3)-d-glucan antibody

HIGHLIGHTS

  • who: from the (UNIVERSITY) have published the research: Structural insights into antigen recognition of an anti-β-(1,6)-β-(1,3)-D-glucan antibody, in the Journal: (JOURNAL) of 20/04/2018
  • what: The work provides an explanation for the specific recognition of triple-helical β-(1,6)-branched β-(1,3)-D-glucans by JoJ48C11 and provides another structure example for anticarbohydrate antibodies. For understanding of the molecular determinants that contribute to the recognition of SCH by JoJ48C11, the authors aimed at obtaining the crystal_structure of a complex with SCH but failed despite extensive attempts. To corroborate . . .

     

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