Structural insights into molecular mechanism for n6-adenosine methylation by mt-a70 family methyltransferase mettl4

HIGHLIGHTS

• who: Qiang Luo from the (UNIVERSITY) have published the paper: Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4, in the Journal: (JOURNAL) of 12/09/2022
• what: The authors report that Arabidopsis METTL4 functions as U2 snRNA MTase for N6-2`-O-dimethyladenosine (m6Am) in_vivo that regulates flowering time, and specifically catalyzes N6-methylation of 2`-Omethyladenosine (Am) within a single-stranded RNA in_vitro. Superposition of Nature Communications | 13:5636 A proposed catalytic mechanism of Am by METTL4 Based on structural and modeling studies, the authors propose a . . .
  

   

  

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