Structural insights into plasticity and discovery of flavonoid allosteric inhibitors of flavivirus ns2b-ns3 protease

HIGHLIGHTS

  • who: Marielena Vogel Saivish and collaborators from the Departamento Doenu00e7as Dermatolu00f3gicas, Infecciosas e Parasitu00e1rias, Faculdade Medicina Campinas, Brazil Nu00facleo Colaborativo Biosistemas, Universidade Federal Jatau00ed, Jatau00ed, Brazil have published the Article: Structural Insights into Plasticity and Discovery of Flavonoid Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease, in the Journal: Biophysica 2023, 3, 71-92. of /2023/
  • what: When the authors compare the amino_acid identity between the NS3pro of DENV-3 and the other flaviviruses (SLEV, WNV, YFV, ILHV, and ROCV) , the authors can see that they have a high identity percentage and also a high TM . . .

     

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