Structural insights into the function-modulating effects of nanobody binding to the integrin receptor αmβ2

HIGHLIGHTS

• who: Rasmus K. Jensen from the Rasmus KJensen1, Henrik Pedersen1, Josefine Lorentzen1, Nick Stub Laursen2, Thomas Vorup-Jensen2, and Gregers Rom Andersen1, * From the Department of Molecular Biology and Genetics, and Department of Biomedicine, Aarhus University, Denmark Edited by Joseph Jez have published the paper: Structural insights into the function-modulating effects ofu00a0nanobody binding to the integrin receptor u03b1Mu03b22, in the Journal: (JOURNAL) of June/15,/2022
• what: The authors show that the receptor headpiece adopts the closed conformation expected to exhibit low ligand affinity. Surprisingly, the authors show that the Nb stimulates the interaction . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.