Structural insights into the role of mutations in amyloidogenesis*

HIGHLIGHTS

• who: Elizabeth M. Baden from the (UNIVERSITY) have published the research work: Structural Insights into the Role of Mutations in Amyloidogenesis*, in the Journal: (JOURNAL) of June/24,/2008
• how: The thermodynamics of the mutants as followed by thermal and chemical denaturation experiments are compared in Table 1.

SUMMARY

LC dimers can be innocuous, but they can also be pathogenic, as in the case of AL. The authors previously examined the structure of LC dimer AL-09, a protein isolated from an AL patient. AL-09 differs from its germline sequence . . .

 



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