Structural insights into the sars-cov-2 omicron rbd-ace2 interaction

HIGHLIGHTS

  • who: Jun Lan from the (UNIVERSITY) have published the article: Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction, in the Journal: (JOURNAL) of 25/01/2022
  • future: In the future study rigorous and quantitative binding free_energy calculations should be performed using more accurate but computational prohibitive approaches such as free_energy perturbation.

SUMMARY

    Received Published online: 13 April 2022 mutations in the Omicron RBD, newly formed interactions occur between Omicron RBD residues (S496, R498 and Y501) and ACE2 residues (D38, Y41 and Q42). Specifically, S496 forms hydrogen_bond with ACE2 . . .

     

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