Structural remodeling of ribosome associated hsp40-hsp70 chaperones during co-translational folding

HIGHLIGHTS

  • who: Yan Chen from the School Tsinghua University University, Beijing, China have published the research: Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors characterize the structures of RAC-containing ribosomal complexes purified through affinity-tagged Zuo1 or nascent chains. The authors characterized the structures of RAC-containing ribosomal complexes prepared from fast growing yeast cells. For the model building of the endogenous 80S-RAC and RNCRAC complexes, the coordinates of the yeast 80S (PDB 4V8Y and 6TNU)73,74 were used . . .

     

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