Structure‐based demystification of radical catalysis by a coenzyme b12 dependent enzyme—crystallographic study of glutamate mutase with cofactor homologues

HIGHLIGHTS

  • who: Structural Biology et al. from the Institute of Molecular Biosciences, University of Graz have published the Article: Structureu2010Based Demystification of Radical Catalysis by a Coenzyme B12 Dependent Enzymeu2014Crystallographic Study of Glutamate Mutase with Cofactor Homologues, in the Journal: (JOURNAL)
  • what: Forschungsartikel environment, the innate chemistry of the organometallic AdoCbl ensures the thermodynamic and kinetic feasibility of the radical generation and a high degree of its reversibility.

SUMMARY

    The initial X-ray structural analysis of AdoCbl bound to substrate-loaded GM[21] has provided an insightful model for the path of . . .

     

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