HIGHLIGHTS
- who: Jiho Song et al. from the College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea, Life Science Research Institute have published the paper: Structure-Activity Relationship of Indole-Tethered Pyrimidine Derivatives that Concurrently Inhibit Epidermal Growth Factor Receptor and Other Angiokinases, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0138823]. September 24, 2015 of March/30,/2015
- what: The authors report the synthesis of an indole derivative of pazopanib using a bioisosteric replacement strategy which was designated MKP101.
- how: The docking results showed that a lipophilic pocket with limited . . .
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