Structure and catalytic mechanism of radical sam methylases

HIGHLIGHTS

• who: Tu-Quynh Nguyen and Yvain Nicolet from the Metalloproteins Unit, UnivGrenoble Alpes, CEA, CNRS, IBS, Grenoble, France have published the article: Structure and Catalytic Mechanism of Radical SAM Methylases, in the Journal: Life 2022, 1732 of /2022/
• what: Instead, the authors focus on the structure-function relationship of the RSMases and how the protein matrix can significantly influence the methylation strategy utilized by these enzymes.
• future: EPR experiments performed on NifB from Methanosarcina acetivorans (MaNifB) in the absence of the K1 or K2 cluster suggested that one of the sulfide ions of . . .
  

   

  

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