Structure- and content-dependent efficiency of cas9-assisted dna cleavage in genome-editing systems

HIGHLIGHTS

  • who: Svetlana V. Baranova et al. from the Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Department of Natural Sciences, Novosibirsk State University, Novosibirsk, Russia have published the article: Structure- and Content-Dependent Efficiency of Cas9-Assisted DNA Cleavage in Genome-Editing Systems, in the Journal: (JOURNAL) of 11/Nov/2022
  • what: The authors attempted to evaluate the effect of formed non-Watson-Crick pairs in a DNA duplex on the efficiency of DNA cleavage in terms of the influence of the structure of the formed partially complementary pairs. The . . .

     

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