Structure and dynamics of an α-fucosidase reveal

HIGHLIGHTS

  • who: Erik H. Klontz from the Institute University of have published the article: Structure and dynamics of an u03b1-fucosidase reveal, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS

SUMMARY

    The D242 Oγ atom is ~19 Å away but located on a loop with very high B-factors that extends into a disordered region in the crystal_structures, which together suggest a high degree of flexibility (Fig 2g). To understand if D242 or one of the other acid/base candidates is capable of moving into the active_site to support catalysis, the authors probed the dynamics of . . .

     

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