Structure and formation of z-dna and z-rna

HIGHLIGHTS

SUMMARY

This newly discovered conformation of nucleic_acids, termed Z-DNA, was nonetheless composed of two antiparallel strands and contained canonical Watson-Crick base_pairs. While arguments of the biological relevance of Z-conformation nucleic_acids were ongoing, proteins that could specifically recognize and bind Z-DNA were discovered, and were subsequently shown to also bind Z-RNA. Since the 1990s, a plethora of biological studies have aimed to secure the relevance of Z-conformation nucleic_acids in biological functions (and references therein). The two values reported for Z-conformation nucleic_acids are for the CpG and GpC steps, respectively . . .

 



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