HIGHLIGHTS
- who: Woo-Ri Shin from the School of Biological Sciences, Chungbuk National University, Chungdaeu2011Ro, Seowonu2011Gu, Cheongju, Republic of Korea have published the article: Structure based innovative approach to analyze aptaprobe-GPC3 complexes in hepatocellular carcinoma, in the Journal: (JOURNAL)
- what: The analysis was performed using a previously described protocol with some modifications (Fig 2A) . The authors designed an aptablot assay for GPC3 detection.
- how: The authors performed 3D structure-based molecular docking simulations which were applied to predict the 3D aptaprobe binding structure followed by validation using in_vitro GPC3 detection. The results indicated . . .
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