Structure-based peptide design to modulate amyloid beta aggregation and reduce cytotoxicity

HIGHLIGHTS

• who: Jitendra Kumar et al. from the Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada have published the article: Structure-Based Peptide Design to Modulate Amyloid Beta Aggregation and Reduce Cytotoxicity, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0129087]. June 12, 2015 of January/28,/2015
• what: Using kinetic analysis of fibril formation electron microscopy and dynamic light scattering characterization of oligomer size distributions the authors demonstrate that in addition to altering fibril structural characteristics these peptides can induce the formation of larger amorphous aggregates which are . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.