HIGHLIGHTS
- who: Julia Buchmueller and colleagues from the German Federal Institute for Risk Assessment, Max-Dohrn-Str8-10, Berlin, Germany Institute of Food Chemistry and Food Biotechnology, Justus Liebig University of Giessen have published the paper: Structure-Dependent Toxicokinetics of Selected Pyrrolizidine Alkaloids In Vitro, in the Journal: (JOURNAL)
- what: The authors examined, if metabolism (including bioactivation) of eight structurally different PAs can also occur in other tissues expressing CYP enzymes possibly exposed to PAs. The study showed structure-dependent passage rates in the Caco-2 model representing the human intestinal barrier for the investigated PAs . . .
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