Structure function analysis of the er-peroxisome contact site protein pex32

HIGHLIGHTS

  • who: Michael Schrader and collaborators from the University of Exeter, United Kingdom have published the article: Structure function analysis of the ER-peroxisome contact site protein Pex32, in the Journal: (JOURNAL)
  • what: The authors show that the second transmembrane (TM) helix harbors ER targeting information. The authors show that the DysF domain is redundant for the role of H. polymorpha Pex32 in peroxisome biology because peroxisome defects are restored upon introduction of a Pex32 construct lacking the DysF domain in pex32 cells. The authors show that cells lacking Pex32 have strongly reduced Pex11 levels, while . . .

     

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