HIGHLIGHTS
- who: Hirdesh Kumar from the National Institute Washington University have published the article: Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases, in the Journal: (JOURNAL) of 22/07/2022
- what: The authors propose naming these two classes of TDases as type 1 TDases for Tet(X)-like TDases; and type 2 TDases for those originally identified in soil metagenomes. The authors investigate Tet(X6) a type 1 TDase first discovered in a Proteus genomospecies20 by determining anhydrotetracyclinefree and anhydrotetracycline-complexed X-ray crystal structures. The authors determined . . .
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