HIGHLIGHTS
- who: Linh Tran from the CNRS have published the article: Structure of ring-shaped Aβ42 oligomers determined by conformational selection, in the Journal: Scientific Reports Scientific Reports
- what: This analysis shows that the compact basin mainly encompasses random coiled structures with residual helical segments, while the extended one covers conformations rich in β-strands. The authors propose here plausible quaternary_structures of such decamers and dodecamers, by performing (with the coarse -grained approach implemented in PTools) single docking calculations of the Aβ42 cyclic pentamer and hexamer models onto themselves, respectively.
- how: This result . . .
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