Structures of atm1 provide insight into [2fe-2s] cluster export from mitochondria

HIGHLIGHTS

• who: Ping Li from the (UNIVERSITY) have published the Article: Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria, in the Journal: (JOURNAL) of 11/07/2022
• what: The authors report a series of cryo-electron microscopy structures of a eukaryotic homolog of human ABCB7, CtAtm1, determined at average resolutions ranging from 2.8 to 3.2 u00c5, complemented by functional characterization and molecular docking in silico. The authors propose that CtAtm1 accepts delivery from glutathione-complexed iron-sulfur clusters. By use of an ortholog from thermophilic filamentous fungus Chaetomium thermophilum, herein . . .
  

   

  

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