Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization

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  • who: Juan F. Bada Juarez from the Oxford University, Mansfield Road, Oxford , TA, UK have published the research work: Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors have determined the crystal_structures of the DA and LA states of the wild-type AR3 photoreceptor, solved to 1.3 and 1.1 Å, respectively. Using quantum mechanical/molecular mechanical (QM/MM) approaches, the study explores the differences between the two states in both the activation_energy barrier for conversion between cis . . .

     

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