Structures of the r-type human cav2.3 channel reveal conformational crosstalk of the intracellular segments

HIGHLIGHTS

• who: Xia Yao from the (UNIVERSITY) have published the Article: Structures of the R-type human Cav2.3 channel reveal conformational crosstalk of the intracellular segments, in the Journal: (JOURNAL) of 12/06/2022
• what: The authors report the cryo-EM structure of human Cav2.3 in complex with u03b12u03b4-1 and u03b23 subunits at an overall resolution of 3.1 u00c5.
• how: CH2II couples PD gating Next the authors compared the structures of u0394CH2 and WT Cav2.3 for detailed analysis.

SUMMARY

The authors report the cryo-EM . . .

 



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