HIGHLIGHTS
SUMMARY
Acute toxicity studies are an integral part of preclinical studies of any new biologically active compound. Acute toxicity was determined by the experimental method of Kerber in_vivo using white nonlinear Wistar rats. Results. According to the results, the studied compound belonged to the V class of toxicity (almost non-toxic), and the resulting LD50 value was 1125 mg/kg. Гостру токсичність визначали за допомогою експериментального методу Кербера in_vivo, використали білих нелінійних щурів лінії Вістар. The aim of the work is to determine acute toxicity in_vivo for the previously obtained compound XPI I-28, namely 2-((4-phenyl-5-(thiophene-3-ylmethyl)-1,2,4-triazole-3-yl) thio . . .
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