Study of late toxicity biomarkers of locally advanced head and neck cancer patients treated with radiotherapy plus cisplatin or cetuximab points to the relevance of skin macrophages (tox-ttcc-2015-01)

HIGHLIGHTS

• What: This study explored tissue biomarkers which could help predict late toxicity. The authors sought to determine the effects of CRT and ERT in healthy tissue from patients with LA-SCCHN. Analysis by late toxicity groups For the analysis of macrophage infiltration, CD68 and CD163 markers were used to identify likely pro-inflammatory and anti-inflammatory macrophages, respectively. The aim of this prospective trial was to study healthy skin at baseline and 3 months after RT to generate hypotheses regarding changes in inflammatory and fibrotic components.
• Who: Antonio Rullan from the Department of Medical Oncology . . .
  

   

  

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