HIGHLIGHTS
- who: Ivan Maslov from the Center for MolecularHasselt University for Polymer Research, Mainz, Germany have published the article: Sub-millisecond conformational dynamics of the A2A adenosine receptor revealed by single-molecule FRET, in the Journal: (JOURNAL) of 17/03/2023
- what: In the PIE approach two spatially overlapped and alternatingly pulsing lasers are focused by the microscope objective to excite donor and acceptor fluorescence consecutively. The authors used smFRET to investigate the conformational dynamics of A2AAR.
- how: The authors introduced a second anticorrelation term in the fitting model for the agonist-bound A2AAR . . .
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