Substrate specificity of gsda revealed by cocrystal structures and binding studies

HIGHLIGHTS

  • who: Qian Jia and collaborators from the MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China have published the paper: Substrate Specificity of GSDA Revealed by Cocrystal Structures and Binding Studies, in the Journal: (JOURNAL)
  • what: GDA and ADA have long been considered attractive drug_targets for anticancer and antibacterial therapies.
  • how: The results indicated that the starting material Gua in a reaction would comous time points. The authors studied the binding modes and deamination activities of AtGSDA both through static crystal_structures and biochemical studies . . .

     

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