Substrate stiffness effect on molecular crosstalk of epithelial-mesenchymal transition mediators of human glioblastoma cells

HIGHLIGHTS

  • who: Bernadette Basilico from the Chiba Cancer Center, Japan Southern Illinois University have published the paper: Substrate stiffness effect on molecular crosstalk of epithelial-mesenchymal transition mediators of human glioblastoma cells, in the Journal: (JOURNAL)
  • what: The authors investigated how the rigidity of the microenvironment influences the EMT and their interrelated pathways to determine a correlation with cell motility and the stiffness of the microenvironment.
  • how: Data were analyzed using Sigma Plot (Systa Software Inc []. As the western blotting results of E-cadherin did not coincide with the immunofluorescence observations the authors hypothesized . . .

     

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